BCP preventing / delaying the onset of neurologic disorders!


This week’s discussion is based on a research paper that Chris found and was only published on 18th of June 2022.  There was one particular conclusion from the research that captured my attention:

BCP may prevent or delay the onset of neurological disorders!


Now that’s pretty exciting news!

Firstly, before we dive too much into the research, let’s just establish what is a neurologic disorders.

neurologic disorder

The reason for neurologic disorders and stress is that the body is under constant stress. The body has to deal with constant changes in your environment, including weather and other people. This can lead to problems in the brain and nervous system, which causes neurologic disorders.

There are many nervous system disorders, here are just a few:

Acute Spinal Cord Injury

Alzheimer’s Disease

Amyotrophic Lateral Sclerosis (ALS)


Bell’s Palsy

Brain Tumors

Cerebral Aneurysm

Epilepsy and Seizures

Guillain-Barré Syndrome


Head Injury


Lumbar Disk Disease (Herniated Disk)


Multiple Sclerosis

Muscular Dystrophy

Neurocutaneous Syndromes

Parkinson’s Disease

Stroke (Brain Attack)

Cluster Headaches

Tension Headaches

Migraine Headaches



Types of Muscular Dystrophy and Neuromuscular Diseases

Myasthenia Gravis 

I’m sure you would agree, anything that can prevent or delay ANY of these would definitely be worth looking into.

Ok then, so what did the researchers have to say?  (My amendments for easier reading)

Inflammation and oxidative stress are interlinked and interdependent processes involved in many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases, and cancer. Therefore, targeting inflammatory pathways may represent a potential therapeutic strategy. Emerging evidence indicates that many phytochemicals extracted from edible plants have the potential to ameliorate the disease phenotypes. In this scenario, ß-caryophyllene (BCP), a bicyclic sesquiterpene, ….. demonstrated to exhibit anti-inflammatory, and antioxidant activities, as well as neuroprotective and mitoprotective effects in different in vitro and in vivo models.

BCP essentially promotes its effects by acting as a selective agonist and allosteric modulator of cannabinoid type-2 receptor (CB2R). BCP can readily cross the BBB (Blood Brain Barrier) and accumulate in brain regions, giving rise to neuroprotective effects by preventing mitochondrial dysfunction and inhibiting activated microglia, substantially through the activation of pro-survival signalling pathways, including regulation of apoptosis and autophagy, and molecular mechanisms related to mitochondrial quality control. 

Findings from different in vitro/in vivo experimental models of Parkinson’s disease and Alzheimer’s disease reported the beneficial effects suggesting that use in treatments may be a promising strategy in the management of neurodegenerative diseases aimed at maintaining mitochondrial homeostasis and ameliorating glia-mediated neuroinflammation.

The conclusion was:

BCP (has) caught a great deal of attention due to (its) ability to reduce OS-induced (Oxidative Stress) free radicals via an antioxidant effect and in managing inflammation through the control of several pathological pathways, as described in different experimental models. Therefore, (BCP) show high BBB permeability and afford a safe approach to protect against the neuronal damage in neurodegenerative diseases via the suppression of microglia-mediated neuroinflammation, as well as in promoting mitochondrial protection. 

Therefore, although further experimental studies and clinical trials are needed to better evaluate the potential neuroprotective efficacy, BCP may represent (as a) promising candidate to prevent or delay the onset of neurological disorders. In this regard, given the lack of toxicity and easy availability from natural resources it will be crucial to explore the chance of their direct employment as supplements in clinical practice.

BCP preventing / delaying the onset of neurologic disorders! » neurologic disorders

The Canna Oils team are regularly asked if we take Canna Oils BCP ourselves.  Our answer is always a definitive YES!  Personally for myself, beside the benefit of a great night sleep and a calmer countenance, I take Canna Oils BCP as a preventative against dis-ease and this research just makes me even more determined to stick with it! 

What about YOU???

Share this article

Related articles

Muscle Inflammation

Last week, we talked about workout recovery.  We looked at the effect of sleep and stress on our recovery and how Canna Oils BCP could potentially help.

Cholesterol, BCP and Healthy Fats

Hey there, Canna Oils family! I had been asked in the past if Beta Caryophyllene (BCP) helps lower cholesterol, and frankly, I didn’t know the answer.  So

Sublingual Advantage

Hey there, Canna Oils family! Today, we’re diving into the wonderful world of sublingual administration and why it’s such a game-changer when it comes to


Product uses, information, promotions and sales, direct to your inbox!

100% free, unsubscribe at any time!