Here is some great information from Dr Steve Best about oxidative stress and the antioxidant characteristics of Beta Caryophyllene(BCP) – [comments and emphasis mine].
Reactive oxygen species (ROS) is a generic term utilised for a variety of particles originated from oxygen that respond with biomolecules by oxidising them, a devastating process. ROS are extensively thought to trigger or exacerbate numerous human pathologies such as neurodegenerative diseases, diabetes, high blood pressure, heart disease, cancer, stroke and lots of other ailments.
Oxidative stress is an imbalance in the body of excessive “oxidants” (oxidising or chemically active, agents, including totally free radicals gotten from the diet plan or produced by the body) and insufficient “antioxidants” (chemically active representatives that are likewise gotten from the diet or produced by the body) and neutralise oxidants. This oversupply of oxidants causes damage to biomolecules, (lipids, proteins, DNA), cells and tissue, eventually contributing to ageing and many chronic diseases including chronic inflammation, arthritis and discomfort, atherosclerosis, cancer, diabetes, heart problem and stroke.
BCP constructs tolerance against stress by enhancing antioxidant power. It reduces oxidative stress by counteracting ROS generation, hindering lipid peroxidation and glutathione depletion, totally free radical scavenging, and enhancing the endogenous antioxidant defence in the tissues of various organs, such as the heart, brain, intestinal tract, stomach, pancreas and blood.
Both oxidative stress and mitochondrial dysfunction are vital trademarks of the early pathological systems of ageing and neurodegenerative disorders, i.e., Alzheimer’s disease, Parkinson’s disease (PD), Several sclerosis (MS), amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD).Research study suggests that BCP has the neuroprotective ability through decreasing oxidative stress and supporting mitochondria and might lead to the discovery of drugs for neurodegenerative disorders. Besides CB2 receptor agonism, BCP has actually been discovered to positively manage PPAR-γ, TLRs and neuroimmune pathways, as possible targets implicated in the security against neuronal loss.
He then goes on to say that more research is need regarding dosage and potential benefits, but nevertheless, these findings are very interesting.