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The ECS – essential & mysterious

The Process of Discovering the Endocannabinoid System!

I like the title of one article I read this week: The Endocannabinoid System – Essential & Mysterious.

I think that sums up the ECS perfectly. So I thought this week we could take a look the mysterious side the of ECS – how it was discovered.

The Process of Discovering the Endocannabinoid System



Many of us have heard of some of the transmitter systems within our bodies, such as the sympathetic nervous system, which gives us our fight-or-flight response. Fewer have heard of the more recently discovered endocannabinoid system (ECS), which is amazing when you consider that the ECS is critical for almost every aspect of our moment-to-moment functioning. The ECS regulates and controls many of our most critical bodily functions such as learning and memory, emotional processing, sleep, temperature control, pain control, inflammatory and immune responses, and eating. The ECS is currently at the centre of renewed international research and drug development.
Below is a short timeline that I found (emphasis mine).

1964 Raphael Mechoulam identified & isolated THC for first time. This soon led to identifying CBD.

1988  the first cannabinoid receptor was found in the brain of a rat.

1990 Lisa Matsuda announces that she and her colleagues have identified a DNA sequence that defines a THC-sensitive receptor in a rat’s brain to the National Academy of Science’s Institute of Medicine….


What was even more surprising is that the receptors were found concentrated in parts of the brain responsible for mental and physiological processes (ie. memory, high cognition, emotion, and motor coordination).

1992 Raphael Mechoulam and National Institute of Mental Health (NIMH) researchers William Devane and Dr. Lumir Hanus discover anandamide, a naturally occurring endogenous cannabinoid found in the human body. Such an endocannabinoid was found to attach to the same receptors as THC, thus being named after the Sanskrit word for bliss. Also nicknamed “the bliss receptor,” anandamide plays a role in memory, pain, depression, and appetite.

1993 a second cannabinoid receptor was identified (this is the CB2 receptor that Canna Oils BCP binds too). This receptor was distributed throughout the immune system and peripheral tissues of the body and exhibited the same reaction to THC as the first receptor.

It was then that researchers realised they were onto something big…

1995 researchers discovered that the two receptors―now deemed the CB1 and CB2 receptors―were found not only in rats, but within thousands of other species―including humans.

In only three decades, humanity has discovered an entirely new system within the human body that regulates nearly all aspects of health…..

I hope you history buffs found that interesting.  Don’t forget to check at past BLOGS on our website – there are heaps of interesting information about the benefits of BCP that you may have missed.

Sources :https://www.hytiva.com/learn/discovering-the-endocannabinoid-system
https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569

The above information is for educational purposes only – not intended as medical advice.

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