Sjorgen’s Syndrome

At the Harrington market, I spoke with a lovely lady that suffers from an autoimmune disorder called Sjorgen’s (Show-grins) Syndrome.  I’d never heard of this condition and promised that I would take a look and see what I could find regarding the benefits of Beta Caryophyllene (BCP) with this syndrome.  So here’s what I discovered….

Sjögren’s Syndrome is a chronic autoimmune disorder that primarily affects the glands responsible for producing saliva and tears. This condition can lead to various uncomfortable symptoms such as dry mouth, dry eyes, and joint pain. While there is no cure for Sjögren’s Syndrome, BCP does have potential to assist with some of the symptoms.

The Power of Beta-Caryophyllene:

BCP is a natural sesquiterpene found in various plants, including cloves, black pepper, and cannabis. It is best known for its anti-inflammatory and antioxidant properties, which make it a great candidate for alleviating symptoms associated with autoimmune conditions like Sjögren’s Syndrome.

1. Anti-Inflammatory Properties:
   • Studies have suggested that BCP exhibits anti-inflammatory effects by interacting with the body’s endocannabinoid system (ECS) – our complex signally system. This interaction may help reduce inflammation in the glands affected by Sjögren’s Syndrome, potentially easing symptoms such as dry mouth.
2. Pain Relief and Neuroprotection:
   • BCP has also shown promise in providing pain relief and neuroprotection (mechanisms and strategies that aim to protect the nervous system from injury and damage). This is particularly relevant for individuals with Sjögren’s Syndrome, as joint pain and nerve-related symptoms are common.
3. Antioxidant Defence:
   • The antioxidant properties of BCP may contribute to protecting the body’s cells from oxidative stress. Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. This is essential for individuals with Sjögren’s Syndrome, as chronic inflammation and autoimmune responses can lead to increased oxidative stress.
4. Potential Interaction with Cannabinoid Receptors:
   • BCP is unique among terpenes as it acts as a selective agonist of the CB2 receptor, part of the ECS. This interaction may modulate immune responses and inflammation, providing a potential avenue for managing autoimmune conditions.

While I couldn’t find any research on the specific impact of BCP on Sjögren’s Syndrome evidence suggests that this natural compound holds promise as a complementary approach to managing symptoms. As we continue to unlock the secrets of natural compounds like BCP, there’s hope for improved quality of life for individuals living with autoimmune conditions like Sjögren’s Syndrome.

Have a great week!

References: Gertsch, J., Leonti, M., Raduner, S., Racz, I., Chen, J. Z., Xie, X. Q., … & Zimmer, A. (2008). Beta-caryophyllene is a dietary cannabinoid. Proceedings of the National Academy of Sciences, 105(26), 9099-9104; Bahi, A., Al Mansouri, S., Al Memari, E., Al Ameri, M., Nurulain, S. M., & Ojha, S. (2014). β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice. Physiology & Behavior, 135, 119-124; Fidyt, K., Fiedorowicz, A., Strządała, L., & Szumny, A. (2016). β-caryophyllene and β-caryophyllene oxide—natural compounds of anticancer and analgesic properties. Cancer Medicine, 5(10), 3007-3017; https://www.medicalnewstoday.com/articles/324863

Disclaimer:  The information in this post is for reference purposes only and not intended to constitute or replace professional medical advice or personal research. Please consult a qualified medical professional before making any changes to your diet, medications or lifestyle. Effects are provided as a guide only.  Statements have not been evaluated by the TGA.